Get access to affordable weight loss medications 100% online
*Rx are up to a medical provider’s discretion & not available in all states. Certain medications are FDA-approved for conditions other than weight loss.. 1 year after starting Found, users have lost an avg. of 12% body weight. Results are based on data from 1,773 users who were active for > 1 year & reported their weight wkly on avg. Separately, in a 72-week clinical trial of tirzepatide (15 mg), paired with diet & exercise, patients with out diabetes & with BMI ≥30, or BMI ≥27 & a weight-related Dx, lost 20% body weight in 1 year. GLP1s have black box warnings. See full risk info below and offer terms here. In-network insurance coverage details, pricing & terms vary. Copays, coinsurance & deductibles may apply. Rx are not included in insurance memberships and are subject to provider discretion. See site for risk info and offer terms. Found is not affiliated with Novo Nordisk A/S., the owner of the registered trademark Ozempic®, Mounjaro®, Rybelsus® and Eli Lilly, the owner of the registered trademarks Zepbound®, Wegovy®. Certain medications are FDA-approved for conditions other than weight.
Membership now as low as $17/month with insurance!*
Ready to get started? Lose weight with Found.
*Ozempic®, metformin are FDA-approved for conditions other than weight loss. Rx are up to a medical provider’s discretion & not available in all states. Medication not included in Plus memberships. In-network insurance coverage, pricing, terms vary. Copays, coinsurance, deductibles may apply. See offer terms here & risk info below. Found is not affiliated with Novo Nordisk A/S., the owner of the registered trademark Ozempic®, Mounjaro®, Rybelsus® and Eli Lilly, the owner of the registered trademarks Zepbound®, Wegovy®.
Lose up to 12% or more of your body weight!* 🎉
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*Real members, paid for appearance. 1 year after starting Found, users have lost an avg. of 12% body weight. Results are based on data from 1,773 users who were active for > 1 year & reported their weight wkly on avg. Separately, in a 72-week clinical trial of tirzepatide (15 mg), paired with diet and exercise, patients with out diabetes and with BMI ≥30, or BMI ≥27 and a weight-related Dx, lost 20% body weight in 1 year. Rx are up to a medical provider’s discretion. GLP1s have black box warnings. See full risk info below.
As Found's Head of Medical Affairs, I help design the clinical protocols that guide the medical care Found's members receive-- care that is guided by the latest advancements in obesity medicine.
Found's clinical team prescribes a wide range of medication.
In the U.S., fewer than 1% of physicians are certified to treat obesity by the American Board of Obesity Medicine. We have access to compassionate, board-certified medical experts who are specially trained in obesity.
*Ozempic®, metformin are FDA-approved for conditions other than weight loss. Rx are up to a medical provider’s discretion & not available in all states. Medication is not included in Plus memberships. In-network insurance coverage, pricing, terms vary. Copays, coinsurance, deductibles may apply. See offer terms here & risk info below. Found is not affiliated with Novo Nordisk A/S., the owner of the registered trademark Ozempic®, Mounjaro®, Rybelsus® and Eli Lilly, the owner of the registered trademarks Zepbound®, Wegovy®.
Found is affordable with or without insurance.
*In-network insurance coverage details, pricing and terms vary. Copays, coinsurance and deductibles may apply. Review offer terms here for more details. Rx are up to a medical provider’s discretion.
Can I pay with my FSA/HSA account?
Yes! You can use your HSA or FSA for any insurance-related costs. These include copays, medications, and other covered services. However, it's up to your insurance provider whether they will accept the charge. You may also be eligible for reimbursement of your membership fee through a health savings account, health reimbursement account, or flexible spending account. Our payment processor will allow you to purchase using an HSA or FSA card. However, it's up to your insurance provider whether they will accept the charge.To determine your eligibility for coverage and your out-of-pocket costs, we kindly recommend that you contact your Insurance Provider. Contact your insurer to determine your eligibility for coverage and your out-of-pocket costs.Please keep in mind that we don't provide itemized receipts if your insurance company asks for them. However, we are happy to we can send you a detailed email regarding your participation in our program along with our receipts.
Do Found’s medications have side effects?
As with any medication, side effects can occur. For many medications, the more common side effects often subside in a few weeks. It’s important to tell your health care provider if you experience any issues when taking a new medication and ask for their medical advice. Detailed side effects and risk information for specific medications are on our medications page.
What medication do clinicians at Found prescribe?
Found-affiliated providers can prescribe a wide range of medications to work with your biology to help you lose weight. Some are FDA-approved anti-obesity medications, and others are FDA-approved for other conditions and prescribed off-label to help people lose weight.
You can learn more about the medicines you may be prescribed on our medications page. Found’s clinicians work with patients to determine the best option for each member, but the ultimate decision as to whether a patient is medically eligible for a medication rests with the provider.
Does Found accept insurance?
Yes! Found partners with many medical insurance carriers across the U.S. to make our care more affordable.
How is Found different from an in-person weight loss clinic?
Found's prescription program is designed by one of the top obesity specialists in the country. Rather than waiting for months for an in-person appointment, you will have access to board-certified medical professionals trained in obesity medicine right away who will be able to personalize a weight care treatment plan to work with your biology from a wide selection of more than 10 different medications (including GLP-1s) that can help guide you throughout your weight loss journey. In addition to access to clinicians, Found also gives you access to health coaches, an exclusive in-app community where you can get support for your journey, and an expert-designed behavior change program to help you make lasting lifestyle changes so that you can reach your goals. Telehealth weight care has fast become one of the most effective and easiest ways to safely access and deliver healthcare. To date, Found has served more than 250,000 people looking to lose weight. With this comprehensive care team at your fingertips, Found gives you the health benefits of in-person care from the comfort of your home.
Medication disclaimers
BLACK BOX WARNING:
Tirzepatide, the active ingredient in Zepbound, is contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take it if you have ever had thyroid cancer. In studies with rodents, tirzepatide caused thyroid tumors, including thyroid cancer; it is not known if it will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Zepbound.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Zepbound, as your diabetes medications may need to be adjusted as you lose weight.
People of childbearing age should use reliable birth control while taking this medication. Use a non-oral contraceptive method (instead of an oral contraceptive). If you use oral contraception, add a barrier method of contraception during the first four weeks after initiation and for four weeks after dose escalation.
This medication may cause fetal harm. Do not take this medication if pregnant, trying to get pregnant, or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least two months before trying. Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Zepbound and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Zepbound and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or a very rapid heartbeat.
Severe hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Zepbound if suspected and promptly seek medical advice.
WARNING
Please get in touch with your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration; it is important to stay well hydrated and drink plenty of fluids while on this medication.
- Kidney problems/kidney failure: vomiting, nausea, and diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; it may sometimes lead to the need for hemodialysis.
- Severe stomach problems, including abdominal bloating or pain, acid reflux, a feeling of fullness after eating just a few bites of food, nausea, and vomiting, including vomiting undigested food eaten a few hours earlier. This may be a symptom of gastroparesis. Also tell your health care provider if you have stomach problems that will not go away.
- An inability to pass gas or stool is a symptom of possible bowel obstruction. Other symptoms may include severe abdominal pain, nausea, and vomiting.
- Thyroid C-cell tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below).
- Pancreatitis: Severe pain in your abdomen or back that will not go away.
- Acute gallbladder disease: Pain in the middle or right upper stomach, fever, white parts of your eyes or skin turning yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder are suspected, further studies are needed.
- Hepatitis, elevated liver enzymes/jaundice.
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems, may worsen in those with a history of diabetic retinopathy.
- Severe gastrointestinal disease: may cause gastrointestinal disease; do not it use if you have a history of severe gastrointestinal disease.
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness): While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams)—drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (e.g., sulfonylurea), it is best to talk to your health care provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate.
- Worsening depression, behavior changes, or suicidality.
- Note: Never share your Zepbound pen with other people.
SIDE EFFECTS INFORMATION
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased lipase or amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Zepbound can interact with alcohol and some prescription and non-prescription drugs and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Zepbound delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, before starting Zepbound please review the timing of taking it with your prescribing doctor as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (e.g., warfarin) should be monitored closely while on Zepbound.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions, and additional information.
To report suspected adverse reactions to Zepbound, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergency, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Mounjaro®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Mounjaro®, as your diabetes medications may need to be adjusted as you lose weight.
Females of reproductive potential should use adequate contraception while taking this medication. It is advised to use a non-oral contraceptive method (instead of oral contraceptive) or, if using oral contraception- add a barrier method of contraception 4 weeks after initiation and 4 weeks after dose escalation.
Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Mounjaro® and call your healthcare provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Mounjaro® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Mounjaro® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Note: Never share the Mounjaro® pen with other people
SIDE EFFECTS INFORMATION
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Mounjaro® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Mounjaro® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Mounjaro®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted.The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Mounjaro®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Mounjaro® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Wegovy®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Wegovy®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Wegovy® and call your healthcare provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Wegovy® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Wegovy® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Never share the Wegovy® pen with other people
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Wegovy® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Wegovy® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Wegovy®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Wegovy®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Wegovy® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Ozempic®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Ozempic®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Ozempic® and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Ozempic® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Ozempic® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Never share the Ozempic® pen with other people
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Ozempic® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Ozempic® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Ozempic®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Ozempic®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Ozempic® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Trulicity®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Trulicity®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Trulicity® and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Trulicity® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Trulicity® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Note: Never share the Trulicity® pen with other people
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Trulicity® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Trulicity® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Trulicity®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted.The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Trulicity®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Trulicity® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Saxenda®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Saxenda®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Saxenda® and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Saxenda® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Saxenda® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Note: Never share the Saxenda® pen with other people
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Saxenda® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Saxenda® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Saxenda®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted.The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Saxenda®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Saxenda® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Victoza®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Victoza®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Victoza® and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Victoza® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Victoza® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your health care provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
- Never share the Victoza® pen with other people
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Injection site reactions
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Victoza® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Victoza® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Victoza®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Victoza®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Victoza® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING:
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome Type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Rybelsus®.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Rybelsus®, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Rybelsus® and call your health care provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Rybelsus® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Rybelsus® if suspected and promptly seek medical advice.
WARNING
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
- Severe nausea and/or vomiting resulting in dehydration- it is important to stay well hydrated and drink plenty of fluids while on this medication
- Kidney problems/kidney failure - vomiting, nausea, diarrhea can cause dehydration and kidney issues and make kidney problems worse in individuals who have pre-existing kidney conditions; may sometimes lead to the need for hemodialysis
- Thyroid C-Cell Tumor: Trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath (see black box warning below)
- Pancreatitis: Severe pain in your abdomen or back that will not go away
- Acute gallbladder disease - Pain in the middle or right upper stomach, fever, white parts of your eyes turn yellow or skin turns yellow, nausea/vomiting. If gallstones or inflammation of the gallbladder is suspected further studies are needed.
- Hepatitis/Elevated liver enzymes/Jaundice
- Diabetic retinopathy problems: Changes in vision in those with Type 2 diabetes, particularly vision problems may worsen in those with a history of diabetic retinopathy
- Severe gastrointestinal disease - may cause gastrointestinal disease; do not use if you have a history of severe gastrointestinal disease
- Signs of low blood sugar (for example, dizziness, weakness, shakiness, jitteriness, headache, anxiety/mood changes, rapid heartbeat, confusion, slurred speech, sweating, or lightheadedness). While this is rare with GLP-1s, if it occurs, please seek in-person care immediately. If you have these symptoms, try having liquid or food containing sugar (around 15-20 grams) —drinking juice, having regular soda, or eating some hard candies right away, as this will help raise your blood sugar quickly. If taken with insulin or an insulin secretagogue (ie sulfonylurea) it is best to talk to your healthcare provider about possibly lowering the dose of these medications to lower the risk of hypoglycemia.
- If you are going under general anesthesia or deep sedation, GLP-1s may make you accidentally breathe food or liquid into your lungs (pulmonary aspiration). Tell the providers who will be performing the procedure that you’re taking a GLP-1 so they can give you instructions to avoid this.
- Increasing heart rate
- Worsening depression, behavior changes, or suicidality
SIDE EFFECTS
Many people experience no side effects. Some of the most common or potential side effects include:
- Nausea
- Constipation
- Vomiting
- Diarrhea
- Abdominal Pain
- Headache
- Indigestion
- Dizziness
- Back pain
- Increased Lipase or Amylase
- Altered taste
- Nasopharyngitis (common cold)
- Passing Gas
- Bloating
- Belching
- Gastroenteritis
- Decreased appetite
- Fatigue
- Gastroesophageal reflux disease
- Low blood sugar (hypoglycemia) in those with Type 2 diabetes
- Upset stomach
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
DRUG INTERACTIONS
As with other medications, Rybelsus® can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Rybelsus® delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Rybelsus®, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted. The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Rybelsus®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Rybelsus® contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
The “black box” on Contrave® warns that this drug may cause suicidal thinking and behavior in young adults, whether or not patients are taking medicines used to treat depression. It may increase the risk of suicidal thoughts in some young adults within the first few months of treatment. Monitor and report worsening or new suicidal thoughts and behaviors to your health care provider. Patients taking bupropion for smoking cessation may also experience changes in mood, psychosis, hallucinations, paranoia, delusions, homicidal ideation, hostility, aggression, anxiety, and panic, as well as suicidal ideation, suicide attempt, and completed suicide, high blood pressure, fast, irregular heartbeats, seizures, acute angle-closure glaucoma, and death.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your health care provider about your medical history prior to taking Contrave®.
The safety and effectiveness of Contrave®, in combination with other products intended for weight loss, including prescription and over-the-counter drugs, and herbal preparations, have not been established.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Contrave®, as your diabetes medications may need to be adjusted as you lose weight.
Do not use this medication if you are or suspect you may be allergic to any of the ingredients in Contrave® including naltrexone and bupropion.
Notify your doctor if you experience:
- Anxiety
- Buzzing or ringing in ears
- Chest discomfort
- Confusion or trouble concentrating
- Depression
- Dry mouth
- Fainting
- Hallucinations
- Headaches
- Hyperventilation
- Impulsivity
- Irregular heartbeats
- Irritability
- Lightheadedness
- Mood or mental changes
- Restlessness
- Seizures
- Shaking
- Skin hives, rashes, or itching
- Suicidal thoughts
- Sweating
- Trouble sleeping
- Unusual tiredness
- Vision changes or eye pain
Stop using Contrave® and get medical help immediately if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Tell your health care provider about your medical history. You should not take Contrave® if you:
- Have uncontrolled high blood pressure
- Have anorexia or bulimia
- Have or have had seizures
- Use other medicines that contain bupropion such as Wellbutrin®, Wellbutrin® SR, Wellbutrin® XL, Aplenzin®, or Zyban®
- Are undergoing an abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and antiepileptic drugs
- Drink a lot of alcohol and abruptly stop drinking
- Have kidney disease
- Have liver disease (it may cause liver dysfunction or hepatitis)
- Are depressed or have suicidal feelings
- Have current or recent (within the past 7-14 days) use of opioids or opiate drugs
You should not take Contrave® under these circumstances either:
- If you’re pregnant, breastfeeding, or planning to become pregnant
- If you’ve taken an MAOI (monoamine oxidase inhibitor), such as Nardil®, Parnate®, or Marplan® in the past 14 days
- If you’re taking any opioids or opiate drugs
- If you’re dependent on opioids or using methadone or buprenorphine
- If you are in opioid withdrawal
If you take opioids or opiates right after stopping Contrave®, you may be more sensitive to them and require lower doses—which poses a risk of overdose. Please talk to your provider before initiating any opioids or opiates after stopping Contrave®.
While some people experience no side effects while taking Contrave®. Some of the most common side effects are:
- Nausea
- Constipation
- Headache
- Vomiting
- Dizziness
- Insomnia
- Dry mouth
- Diarrhea
- Anxiety
- Hot flushes
- Fatigue
- Tremors
- Upper abdominal pain
- Viral gastroenteritis
- Influenza (flu)
- Tinnitus (ringing in the ears)
- Urinary tract infection
- Excessive sweating
- Irritability
- Increased blood pressure
- Changes in taste and smell
- Rashes
- Muscle strains
- Palpitations (heart racing)
Additional but less common side effects may include:
Fast heart rate, heart attack, dizziness, motion sickness, lower abdominal pain, gas, lip swelling, rectal bleeding, hernia, inflamed gallbladder, pneumonia, staph infection, kidney infection, increased blood creatinine, increased hepatic enzymes, decreased hematocrit, feeling jittery, feeling abnormal, feeling weak or a loss of energy, thirst, feeling hot, disturbance in attention, feeling sleepy, tremors, balance disorder, impaired memory, amnesia, abnormal dreams, nervousness, feeling spacey, tension, agitation, mood swings, abnormal and frequent urination, dehydration, bulging or herniated discs, jaw pain, feeling faint, hair loss, erectile dysfunction, vaginal dryness, and irregular menstrual cycles (periods).
These symptoms often subside as your body adjusts to the medication. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
If you take diabetes medications, please discuss this with your prescribing clinician before taking Contrave® since your diabetes medications may need to be adjusted as you lose weight.
As with other medications, Contrave® can interact with alcohol and certain prescription and OTC medications and herbal products. Some drugs and other substances can interact with Contrave®, including alcohol, MAOIs (like isocarboxazid, linezolid, phenelzine, selegiline, or tranylcypromine), drugs that increase dopamine levels in your system (like levodopa and amantadine), drugs that affect the central nervous system (like antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medication), drugs for depression or anxiety, antipsychotics, theophylline, systemic corticosteroids, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder (ADHD), medicine for seizures or barbiturates, muscle relaxants, anesthetics, including some dental anesthetics, dextromethorphan, diarrhea medication (such as diphenoxylate), disulfiram, opioid pain or cough relievers (such as codeine and hydrocodone), thioridazine.
Avoid drinking alcohol while taking Contrave®.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions, and additional information.
To report suspected adverse reactions to Contrave®, contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
BLACK BOX WARNING: METFORMIN MAY CAUSE LACTIC ACIDOSIS
Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. Symptoms included malaise, myalgias, respiratory distress, somnolence, dizziness, changes in heart rate/rhythm, and abdominal pain. Laboratory abnormalities included elevated blood lactate levels, anion gap acidosis, increased lactate/pyruvate ratio; and metformin plasma levels generally >5 mcg/mL. In more than 20,000 patient-years exposure to metformin in clinical trials, there were no reports of lactic acidosis. Reported cases have occurred primarily in diabetic patients with significant renal insufficiency, including both intrinsic renal disease and renal hypoperfusion, often in the setting of multiple concomitant medical/surgical problems and multiple concomitant medications.
Risk factors include renal impairment, concomitant use of certain drugs, age ≥65 years old, radiological studies with contrast, surgery and other procedures, hypoxic states, excessive alcohol intake, and hepatic impairment. Lactic acidosis is a medical emergency and requires immediate treatment in the hospital.
WARNING
Before using metformin, tell your health care provider about your medical history, especially if you have:
- kidney disease
- heart disease or congestive heart failure
- liver disease
- metabolic acidosis or diabetic ketoacidosis
- high ketone levels in your blood or urine
- you use insulin or other diabetes medications
Talk to your health care provider if you are planning to become pregnant or if pregnant or breastfeeding. Avoid alcohol while taking this medication. Talk to your health care provider about discontinuing metformin prior to a surgical procedure or an iodinated contrast imaging procedure. Stop metformin and notify your health care provider immediately if you have an illness with severe diarrhea and/or vomiting resulting in dehydration.
SIDE EFFECTS
Many people experience no side effects while taking metformin. The most common side effects of metformin include:
- diarrhea
- nausea/vomiting
- upset stomach (gas, bloating, and stomach cramps)
These symptoms may subside after the body adjusts to the medication. Taking your medicine with the evening meal can help reduce these side effects.
Additional but rare side effects include:
- low blood sugar (hypoglycemia)
- feeling cold
- unusual muscle pain
- dizziness
- slow or irregular heart rate
- trouble breathing
- metallic taste
- changes to nails on fingers and toes
- Low b12 levels
DRUG INTERACTIONS
As with other medications, metformin can interact with alcohol and certain medications, including angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, corticosteroids, hormone replacement therapy and estrogens, oral contraceptives, carbonic anhydrase inhibitors, nifedipine, thiazides or furosemide and other diuretics, phenothiazines, phenytoin, nicotinic acid (niacin), multidrug and toxin extrusion inhibitors, sympathomimetics, calcium channel blockers, isoniazid (antibiotic for tuberculosis), insulin and glyburide or other medications for diabetes, and medications for thyroid disease.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to metformin contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
WARNING
DO NOT take zonisamide if you have an allergy to sulfa drugs. A potentially fatal reaction can occur including a life threatening skin rash or a blood cell condition.
Before using zonisamide, tell your health care provider about your medical history, especially if you have:
- kidney disease
- liver disease
- long-term diarrhea
- lung or breathing problems
- metabolic acidosis or diabetic ketoacidosis
- high ketone levels in your blood or urine
- you use insulin or other diabetes medications
- history of psychiatric disorders or suicidal thoughts
Talk to your health care provider if you are planning to become pregnant or if pregnant or breastfeeding. Avoid alcohol and stay well hydrated while taking this medication. Do not drive, operate heavy machinery or perform any hazardous task until the effects of this medication are known to you. Tell your health care provider right away if you experience eye pain, changes in vision, eye swelling or redness, yellowing of the eyes, confusion, difficulty concentrating, suicidal thoughts, memory problems, trouble thinking clearly, agitation, irritability, speech problems, decreased sweating, sudden flank pain, painful urination, dark urine, increased fatigue, skin rash, faintness, easy bruising, irregular or fast heartbeat, bone pain, rapid breathing, dizziness, or stomach pain that is severe or that lasts more than a few days.
SIDE EFFECTS
Many people experience no side effects while taking zonisamide. The most common side effects of zonisamide include:
- dizziness and lightheadedness
- fatigue and drowsiness
- language and speech difficulty
- metallic taste
- nausea
Other possible side effects include:
- trouble sleeping
- lack of coordination
- loss of appetite and weight loss
- diarrhea
- double vision
- mood changes such as depression or irritability
- difficulty concentrating
These symptoms may subside after your body adjusts to the medication.
DRUG INTERACTIONS
As with other medications, zonisamide can interact with certain medications, including carbonic anhydrase inhibitors (such as acetazolamide), orlistat (if using zonisamide for a seizure disorder), phenobarbital, primidone, rifamycins, glucocorticoids, and St. John's wort.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information. Do not stop taking this medication without consulting your healthcare provider because some conditions may become worse when the drug is suddenly stopped.
To report suspected adverse reactions to zonisamide contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
WARNING
Before using topiramate, tell your health care provider about your medical history, especially if you have:
- narrow angle glaucoma and nearsightedness
- kidney problems, such as kidney stones
- liver problems
- depression or thoughts of suicide
- lung or breathing problems
- metabolic acidosis
- high blood ammonia levels
- long-term diarrhea
- low body temperature
- a diet high in fat and low in carbohydrates, aka a ketogenic diet
- brittle bones
Topiramate may cause some people to sweat less. It is recommended to avoid alcohol and stay well hydrated while taking this medication.This drug may make you dizzy or drowsy or impair your judgment. Please do not drive, operate heavy machinery, or perform any hazardous task until the effects of topiramate are known to you. For anyone taking diabetes medications, please have a discussion with your prescribing clinician prior to taking topiramate as your diabetes medications may need to be adjusted as you lose weight.
Topiramate may also cause birth defects (particularly there is a risk of cleft lip and/or palate and low birth weight). Topiramate may cause breakthrough bleeding. DO NOT take topiramate if you are planning to become pregnant or if pregnant or breastfeeding.
SIDE EFFECTS
Many people experience no side effects while taking topiramate. Some of the most common side effects (but not extremely frequent) are:
- anorexia
- weight loss
- dizziness
- fatigue or drowsiness
- difficulty with concentration and psychomotor slowing
- speech difficulty
- nervousness
- tingling or prickling sensations
- abnormal vision
- fever
Additional side effects include:
- difficulty with memory
- changes in taste
- diarrhea
- numbness
- nausea
- abdominal pain
- upper respiratory tract infection
- hair loss
- changes in mood/suicidal thoughts
These symptoms may subside after the body adjusts to the medication.
DRUG INTERACTIONS
As with other medications, topiramate can interact with alcohol, marijuana and certain medications, including antiepileptic drugs, CNS depressants, oral contraceptives, lithium, other carbonic anhydrase inhibitors, hydrochlorothiazide, pioglitazone and amitriptyline. Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to topiramate contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.
