How much does metformin cost?

According to Harvard Health Publishing, European scientists first discovered metformin’s impact on blood glucose in 1918. But Americans were unable to get prescriptions for it as a diabetes treatment until 1995, shortly after it won FDA approval. Now metformin is the most commonly used oral type 2 diabetes medication in the world. 

These days, metformin (also known as metformin hydrochloride) is making a splash in a different health area: weight loss. The generic prescription drug is often prescribed off-label to treat people who are overweight or have obesity. Metformin’s brand-name versions include Fortamet® and Glumetza®*. 

History and brand-names aside, though, if you’re considering using this prescription medication for weight loss, we know you have one big question on your mind: What will metformin cost me? 

What does metformin cost out-of-pocket?

The cost of metformin and, indeed, all drugs, depends on a variety of factors. Among them are where you live, the pharmacy you use for prescriptions, your insurance coverage, your prescribed dosage, and whether you use generic versions or name-brand medication. 

GoodRx lists the retail price for 60 (500-milligram) tablets of non-brand-name metformin at an average of $10 to $30, while SingleCare lists prices ranging from $8 to $43 without insurance or coupons. Note that FDA-approved generic versions of metformin will typically cost less out of pocket. Reviewing your insurance coverage, seeking discount cards, or considering a 90-day supply may lower the overall cash price of metformin.

Does insurance coverage include metformin for weight loss? 

For those diagnosed with type 2 diabetes, insurers—including Medicaid and Medicare—will often cover chronic conditions. Unfortunately, according to the Obesity Medicine Association, insurance carriers do not typically cover weight loss medications. 

Insurance plans vary widely, however, so it is worth discussing your options with a health care professional and contacting your insurance carrier to understand all coverage details. If your insurance covers metformin, ask about other out-of-pocket costs you may incur, including co-pays. 

What is the average prescription for metformin? 

Available in either immediate- or extended-release tablets, metformin is taken by mouth and comes in strengths ranging from 500 to 1,000 milligrams. Based on your specific needs, a health care provider will help you determine which form, what strength, and how frequently you should take metformin.

If you are eligible for metformin for weight loss, your doctor will recommend a treatment plan that includes dose strength and how often you should take metformin each day. You can seek medical advice from your doctor or pharmacist to determine if a generic form of metformin or a brand name like Fortamet or Glumetza is best. After starting metformin, if you experience any side effects, contact your medical professional to determine if changes are needed. 

Common metformin side effects include gastrointestinal issues (diarrhea, constipation, mild stomach pain or cramping, bloating, gas, indigestion, heartburn), a metallic taste in the mouth, headache, nail changes, flushing of the skin, and muscle pain. More serious but less common side effects include chest pain, severe stomach pain, hypoglycemia, dizziness, and shortness of breath. 

The FDA also has a “black box warning” on metformin as it carries a serious safety risk of lactic acidosis. This rare but potentially fatal condition is when too much lactic acid builds up in the blood. It can lead to low blood pressure, breathing issues, heart failure, and even death.

Additionally, metformin may stimulate ovulation in those with PCOS or who are premenopausal and may increase the risk of unintended pregnancy. If you’re in a sexual relationship that can result in pregnancy, use at least one form of birth control while taking metformin unless you’re planning on getting pregnant. Find detailed side effect and risk information on our dedicated metformin page. 

Can I lose weight on metformin? 

While its intended use is to treat type 2 diabetes, various research studies document metformin’s impact on weight loss. Although it’s not FDA-approved for weight loss, the anti-diabetic drug can be an effective option for those with biological barriers to other types of weight loss treatments. Metformin works to suppress appetite by helping regulate blood sugar levels and encouraging the body to use insulin more efficiently. Recent studies have shown that metformin may influence the body’s production of an “anti-hunger” molecule similar to those naturally produced after intense exercise, which can help suppress appetite.

Individual results vary, but some using metformin (including Found subscriber Terrance) have experienced weight loss on metformin in as little as a few months. In one study comparing metformin use with intensive lifestyle intervention or placebo, 28.5% of those on metformin lost 5% or more of their body weight in one year, compared with 13% of those taking placebo. Participants who continued taking metformin for another five to 14 years maintained an average weight loss of 6.2% of their body weight. A treatment plan that pairs prescription weight loss medication with healthy lifestyle habits may improve your chances for long-term results. 

Is metformin my only option? 

Just as each body is different, so, too, is each weight loss journey. While metformin can be a safe and effective option for weight loss, we recognize that it won’t be a match for everyone. Found’s medication lineup includes GLP-1s, non-GLP-1s, and compounded medications to help you find the “one” that works with your unique biology and makes a difference for you. 

Your Found-affiliated health care provider will review your genetic makeup, medical history, and other facts to offer personalized medical advice and a prescription medication weight-loss plan tailored to your needs. Clinicians trained in obesity medicine helped develop our science-backed approach to encourage weight loss that works with your body—not against it. 

At Found, we strive to increase access and affordability for those who are overweight and those with obesity who may benefit from prescription weight loss medication. Whether it’s metformin or another drug, we’ll work with you to find the prescription that fits your lifestyle and your budget. 

Found clinicians work with patients to determine the best option for each subscriber, but the ultimate decision as to whether a patient is qualified for a medication rests with the provider.

*Previous metformin brand names Glucophage and Riomet have been discontinued for use in the U.S.

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