Trulicity® mimics GLP-1 in the body and delays gastric emptying, helping you feel fuller longer and reducing appetite. Minimizing blood sugar levels also reduces appetite.
This medication is part of a class of medications called Glucagon like peptide-1 (GLP-1s) which can help you feel fuller and helps to stabilize blood sugar levels. They can also help with cravings and appetite and have been found to be very effective for weight loss. Trulicity® is FDA-approved for the treatment of type II diabetes and to decrease the risk of cardiac complications in adults with type II diabetes and in those who have heart disease.
Trulicity® comes in an injection given at doses which start at 0.75 mg once weekly. Dosing instructions vary according to weight, tolerability, other factors, and should be discussed with your healthcare provider.
Nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, heartburn, and dizziness.
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Trulicity® is only FDA-approved to treat type 2 diabetes. Medication prescriptions are up to a medical provider’s discretion and may not be appropriate for everyone.
Eli Lilly and Company - Highlights of Prescribing Information
GLP-1s are contraindicated in individuals with a history of medullary thyroid carcinoma, a family history of such, or in patients with multiple endocrine neoplasia syndrome type 2. Do not take them if you have ever had thyroid cancer. In studies with rodents, GLP-1s caused thyroid tumors, including thyroid cancer; it is not known if they will cause thyroid tumors or cancer in humans. Please notify your doctor ASAP if you develop trouble swallowing, hoarseness, a lump or swelling in your neck, or shortness of breath.
If you experience a medical emergency, call 911 or go to the nearest emergency room.
Tell your healthcare provider about your medical history prior to taking Trulicity.
Avoid alcohol while taking this medication. If you’re taking diabetes medications, please discuss this with your prescribing doctor before starting Trulicity, as your diabetes medications may need to be adjusted as you lose weight.
Use adequate contraception while taking this medication. Do not take this medication if pregnant, trying to get pregnant or breastfeeding. If you plan to become pregnant, this medication needs to be stopped at least 2 months before trying. This medication may cause fetal harm.
Notify your doctor if you have kidney, liver, or pancreas problems.
Stop using Trulicity and call your healthcare provider immediately if you have severe stomach or abdomen pain that will not go away, with or without vomiting.
Stop using Trulicity and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
Serious hypersensitivity reactions (e.g., anaphylaxis and angioedema) have been reported. Discontinue Trulicity if suspected and promptly seek medical advice.
Please contact your doctor ASAP and seek in-person care immediately if a side effect becomes problematic or you experience:
Many people experience no side effects. Some of the most common or potential side effects include:
These symptoms often subside as your body adjusts to the medications. Please notify your provider if side effects persist. For a complete list of side effects, review the medication packaging inserts.
As with other medications, Trulicity can interact with alcohol and certain prescription and non-prescription medications and herbal products. The risk of hypoglycemia is increased when combined with insulin or insulin secretagogues such as sulfonylureas. Trulicity delays gastric emptying and may impact the absorption of oral medications. If you are on thyroid hormone medication, prior to starting Trulicity, please review the timing of taking your thyroid hormone medication with the doctor who prescribes it as it may need to be adjusted.The drug levels of medications with narrow therapeutic windows (ie warfarin) should be monitored closely while on Trulicity.
Please consult the pharmaceutical packaging for a full list of side effects, warnings, interactions and additional information.
To report suspected adverse reactions to Trulicity contact the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
In case of emergencies, please call 911 or go to the nearest emergency room.